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Black cbd oil for cancer

What Is Rick Simpson Oil?

Rick Simpson Oil (RSO) is a highly potent, viscous, dark-brown/black oil. RSO results from stripping the cannabis plant’s trichomes, which are rich in therapeutic cannabinoids and terpenes. The final product is a powerhouse of healing compounds including potent tetrahydrocannabinol (THC).

Created by a Canadian scientist named Rick Simpson, RSO originally helped its namesake treat an aggressive form of skin cancer. Simpson was diagnosed with basal cell carcinoma and delved into research on the impact of THC on cancer cells. From there, he created a cannabis oil that he applied to his skin. After only four days, his cancerous cells were reportedly gone.

Sold on the healing effects of medical marijuana, Simpson cultivated his own cannabis, harvested his own plants, and created more of that cannabis-infused oil, known today as RSO. Learn about how RSO works and how to use RSO as a natural wellness supplement.

How It Works

RSO is similar to a highly purified form of hashish, where a plant’s resin and trichomes are separated from the plant itself to create a cannabinoid-concentrated product. The theory is that the potent mix of highly concentrated cannabinoids and terpenes can help treat conditions like cancer by effectively “soaking” the body’s cells with cannabinoids, meaning that the oil can help fight cancerous cells throughout the body.

There are significant differences between Rick Simpson Oil and regular cannabis oil.

Rick Simpson Oil vs. Cannabis Oil: Differences and Similarities

Cannabis oil usually refers to the infusion of cannabis into an oil, usually olive, coconut or MCT oil. In contrast, RSO is an oily concentrate made from separating the plant’s cannabinoids from the plant material. RSO is therefore more similar to hash or other cannabis concentrates.

One similarity between RSO and cannabis oil is that both products are full-spectrum, meaning that they contain a range of chemical compounds including psychoactive THC. In fact, RSO usually contains higher levels of THC than ordinary cannabis oil. The dense THC concentrations of RSO make the product more potent than most cannabis oils.

How to Make Rick Simpson Oil

The process of making RSO involves:

  • Mixing together highly purified alcohol with cannabis to create a solvent
  • Straining the solvent to get rid of extra plant material
  • Heating the solvent (avoiding any naked flames) to get rid of all the alcohol and any other contaminants present in the solvent
  • The result is a thick, sticky, brown-black oil that can be used as you wish, including in edible form

Please note that making RSO at home is potentially dangerous (and illegal in many places), so we do not recommend that you attempt the process.

Benefits and Uses

While modern research has shown RSO is effective in fighting cancer in conjunction with other therapies, RSO can treat a laundry list of other conditions as well. Some of the ailments RSO has also been shown to be effective with include, but are not limited to, the following:

Download Guide To Anxiety and Medical Cannabis

Generally, while dosing may be different for everyone depending on age, sex, and other factors of physical health, the rule of thumb when it comes to RSO is 60 grams over 90 days. Patients should start with three doses a day of only a small drop (equivalent to a grain of rice) applied either topically or ingested in some way every eight or so hours.

From there, the patient should double their dose every four or so days. Then, after about five weeks, the patient should up their dose to a gram of oil per day until all 60 grams have been used. This is the treatment usually recommended for those suffering from cancer. While there is some anecdotal evidence that this dosing regime works, others may benefit from different dosages and ingestion methods.

If you’re going to smoke or vape RSO instead of ingesting or using it topically, you need to make sure that particular oil is right. Always check with your budtender at the dispensary you’re buying from and, of course, if you’re making it yourself make sure to burn off the alcohol completely before smoking it. However, we at Leafwell do not recommend this ingestion method, as the results can be dangerous and combustible.

If you’re cooking with RSO, one popular staple is a cannabutter or cannabis cooking oil. From there, you can swap your cannabis-infused product with the normal one in recipes to create RSO-infused edibles. You can even mix the oil into sauces, dips, salad dressings and beverages.

But remember: start low and go slow. Cannabis edibles, especially those made with RSO, can be extraordinarily potent, so use less than you think you need.

Download Free Guide to Marijuana and Insomnia

Potential Risks and Interactions

Rick Simpson Oil carries the same risks as any THC product, but perhaps even more so as RSO is generally higher in the intoxicating cannabinoid. The risks and side effects of THC include:

  • Headache
  • Nausea and/or vomiting
  • Mood swings
  • Paranoia
  • Anxiety
  • Accelerated heart rate
  • Coordination problems
  • Red eyes
  • Delayed reaction times
  • Fatigue
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Avoid driving or operating any kind of machinery when using RSO and other THC products. Seek medical attention if you experience moderate or severe side effects from using Rick Simpson Oil.

Furthermore, there are many potential drug interactions to be aware of before you use RSO with any other medication. Antidepressants, opioids and sedatives are just a few types of drugs that can negatively interact with Rick Simpson Oil.

Frequently Asked Questions

Does Rick Simpson Oil (RSO) contain THC?

Yes, Rick Simpson Oil is exceptionally high in THC, often containing concentrations of 60 percent or higher. If you are looking for products that have no THC, CBD topicals (especially those made from CBD isolate) are your best bet.

Why is RSO (Rick Simpson Oil) banned in many countries?

RSO is banned in many countries where cannabis and THC are illegal. There may also be concerns about advertising Rick Simpson Oil as a “cure” for cancer when no such cure exists. RSO may be beneficial for some people with cancer, but it cannot legally or ethically be classified as a remedy.

Is there any evidence that Rick Simpson Oil works?

There is some evidence that RSO may be effective for certain individuals, but further research is crucial. As more federally-funded research develops on the endocannabinoid system (ECS) and the overall impact of medical cannabis, we’ll get a fuller understanding of how RSO can help treat diseases including cancer.

Use Rick Simpson Oil and other THC cannabis products legally with a medical marijuana card. The team of doctors at Leafwell are here to meet with you online and get you started on your application.

Cannabis, CBD oil and cancer

Cannabis is a plant and a class B drug. It affects people differently. It can make you feel relaxed and chilled but it can also make you feel sick, affect your memory and make you feel lethargic. CBD oil is a chemical found in cannabis.

Summary:

  • Cannabis has been used for centuries recreationally and as a medicine.
  • It is illegal to possess or supply cannabis as it is a class B drug.
  • Research is looking at the substances in cannabis to see if it might help treat cancer.
  • There are anti sickness medicines that contain man-made substances of cannabis.

What are cannabis and cannabinoids?

Cannabis is a plant. It is known by many names including marijuana, weed, hemp, grass, pot, dope, ganja and hash.

The plant produces a resin that contains a number of substances or chemicals. These are called cannabinoids. Cannabinoids can have medicinal effects on the body.
The main cannabinoids are:

  • Delta-9-tetrahydrocannabinol (THC)
  • Cannabidiol (CBD)

THC is a psychoactive substance that can create a ‘high’ feeling. It can affect how your brain works, changing your mood and how you feel.

CBD is a cannabinoid that may relieve pain, lower inflammation and decrease anxiety without the psychoactive ‘high’ effect of THC.

Different types of cannabis have differing amounts of these and other chemicals in them. This means they can have different effects on the body.

Cannabis is a class B drug in the UK. This means that it is illegal to have it, sell it or buy it.

CBD oil, cannabis oil and hemp oil

There are different types of oil made from parts of the cannabis plant. Some are sold legally in health food stores as a food supplement. Other types of oil are illegal.

CBD oil comes from the flowers of the cannabis plant and does not contain the psychoactive substance THC. It can be sold in the UK as a food supplement but not as a medicine. There is no evidence to support its use as a medicine.

Cannabis oil comes from the flowers, leaves and stalks of the cannabis plant. Cannabis oil often contains high levels of the psychoactive ingredient THC. Cannabis oil is illegal in the UK.

Hemp oil comes from the seeds of a type of cannabis plant that doesn’t contain the main psychoactive ingredient THC. Hemp seed oil is used for various purposes including as a protein supplement for food, a wood varnish and an ingredient in soaps.

Why people with cancer use it

Cannabis has been used medicinally and recreationally for hundreds of years.

There has been a lot of interest into whether cannabinoids might be useful as a cancer treatment. The scientific research done so far has been laboratory research, with mixed results, so we do not know if cannabinoids can treat cancer in people.

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Results have shown that different cannabinoids can:

  • cause cell death
  • block cell growth
  • stop the development of blood vessels – needed for tumours to grow
  • reduce inflammation
  • reduce the ability of cancers to spread

Scientists also discovered that cannabinoids can:

  • sometimes encourage cancer cells to grow
  • cause damage to blood vessels

Cannabinoids have helped with sickness and pain in some people.

Medical cannabis

This means a cannabis based product used to relieve symptoms.

Some cannabis based products are available on prescription as medicinal cannabis. The following medicines are sometimes prescribed to help relieve symptoms.

Nabilone (Cesamet)

Nabilone is a drug developed from cannabis. It is licensed for treating severe sickness from chemotherapy that is not controlled by other anti sickness drugs. It is a capsule that you swallow whole.

Sativex (Nabiximols)

Sativex is a cannabis-based medicine. It is licensed in the UK for people with Multiple Sclerosis muscle spasticity that hasn’t improved with other treatments. Sativex is a liquid that you spray into your mouth.

Researchers are looking into Sativex as a treatment for cancer related symptoms and for certain types of cancer.

How you have it

Cannabis products can be smoked, vaporized, ingested (eating or drinking), absorbed through the skin (in a patch) or as a cream or spray.

CBD oil comes as a liquid or in capsules.

Side effects

Prescription drugs such as Nabilone can cause side effects. This can include:

  • increased heart rate
  • blood pressure problems
  • drowsiness
  • mood changes
  • memory problems

Cannabis that contains high levels of THC can cause panic attacks, hallucinations and paranoia.

There are also many cannabis based products available online without a prescription. The quality of these products can vary. It is impossible to know what substances they might contain. They could potentially be harmful to your health and may be illegal.

Research into cannabinoids and cancer

We need more research to know if cannabis or the chemicals in it can treat cancer.

Clinical trials need to be done in large numbers where some patients have the drug and some don’t. Then you can compare how well the treatment works.

Many of the studies done so far have been small and in the laboratory. There have been a few studies involving people with cancer.

Sativex and temozolomide for a brain tumour (glioblastoma) that has come back

In 2021, scientists reported the final results of a phase 1 study to treat people with recurrent glioblastoma (a type of brain tumour that has come back). The study looked at Sativex in combination with the chemotherapy drug temozolomide.

Researchers found that adding Sativex caused side effects, which included, vomiting, dizziness, fatigue, nausea and headache but patients found the side effects manageable.

They also observed that 83 out of 100 people (83%) were alive after one year using Sativex, compared to 44 out of 100 people (44%) taking the placebo.

However, this phase 1 study only involved 27 patients, which was too small to learn about any potential benefits of Sativex. The study wanted to find out if Sativex and temozolomide was safe to take by patients.

Researchers have now started a larger phase 2 trial called ARISTOCRAT, to find out if this treatment is effective and who might benefit from it. Speak to your specialist if you want to take part in a clinical trial.

Sativex and cancer pain

There are trials looking at whether Sativex can help with cancer pain that has not responded to other painkillers.

The results of one trial showed that Sativex did not improve pain levels. You can read the results of the trial on our clinical trials website.

Cancer and nausea and vomiting

A cannabis based medicine, Nabilone, is a treatment for nausea and vomiting.

A Cochrane review in 2015 looked at all the research available looking into cannabis based medicine as a treatment for nausea and sickness in people having chemotherapy for cancer. It reported that many of the studies were too small or not well run to be able to say how well these medicines work. They say that they may be useful if all other medicines are not working.

Other research

A drug called dexanabinol which is a man made form of a chemical similar to that found in cannabis has been trialled in a phase 1 trial. This is an early trial that tries to work out whether or not the drug works in humans, what the correct dose is and what the side effects might be. The results are not available yet. You can read about the trial on our clinical trials database.

Word of caution

Cannabis is a class B drug and illegal in the UK.

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There are internet scams where people offer to sell cannabis preparations to people with cancer. There is no knowing what the ingredients are in these products and they could harm your health.
Some of these scammers trick cancer patients into buying ‘cannabis oil’ which they then never receive.

You could talk with your cancer specialist about the possibility of joining a clinical trial. Trials can give access to new drugs in a safe and monitored environment.

More information

The science blog on our website has more information about cannabis and cancer.

Daily use of cannabidiol (‘CBD’) oil may be linked to lung cancer regression

It may be worth exploring further the use of cannabidiol (‘CBD’) oil as a potential lung cancer treatment, suggest doctors in BMJ Case Reports after dealing with a daily user whose lung tumour shrank without the aid of conventional treatment.

The body’s own endocannabinoids are involved in various processes, including nerve function, emotion, energy metabolism, pain and inflammation, sleep and immune function.

Chemically similar to these endocannabinoids, cannabinoids can interact with signalling pathways in cells, including cancer cells. They have been studied for use as a primary cancer treatment, but the results have been inconsistent.

Lung cancer remains the second most common cancer in the UK. Despite treatment advances, survival rates remain low at around 15% five years after diagnosis. And average survival without treatment is around 7 months.

The report authors describe the case of a woman in her 80s, diagnosed with non-small cell lung cancer. She also had mild chronic obstructive pulmonary disease (COPD), osteoarthritis, and high blood pressure, for which she was taking various drugs.

She was a smoker, getting through around a pack plus of cigarettes every week (68 packs/year).

Her tumour was 41 mm in size at diagnosis, with no evidence of local or further spread, so was suitable for conventional treatment of surgery, chemotherapy, and radiotherapy. But the woman refused treatment, so was placed under ‘watch and wait’ monitoring, which included regular CT scans every 3-6 months.

These showed that the tumour was progressively shrinking, reducing in size from 41 mm in June 2018 to 10 mm by February 2021, equal to an overall 76% reduction in maximum diameter, averaging 2.4% a month, say the report authors.

When contacted in 2019 to discuss her progress, the woman revealed that she had been taking CBD oil as an alternative self-treatment for her lung cancer since August 2018, shortly after her original diagnosis.

She had done so on the advice of a relative, after witnessing her husband struggle with the side effects of radiotherapy. She said she consistently took 0.5 ml of the oil, usually three times a day, but sometimes twice.

The supplier had advised that the main active ingredients were Δ9-­tetrahydrocannabinol (THC) at 19.5%, cannabidiol at around 20%, and tetrahydrocannabinolic acid (THCA) at around 24%.

The supplier also advised that hot food or drinks should be avoided when taking the oil as she might otherwise feel stoned. The woman said she had reduced appetite since taking the oil but had no other obvious ‘side effects’. There were no other changes to her prescribed meds, diet, or lifestyle. And she continued to smoke throughout.

This is just one case report, with only one other similar case reported, caution the authors. And it’s not clear which of the CBD oil ingredients might have been helpful.

“We are unable to confirm the full ingredients of the CBD oil that the patient was taking or to provide information on which of the ingredient(s) may be contributing to the observed tumour regression,” they point out.

And they emphasise: “Although there appears to be a relationship between the intake of CBD oil and the observed tumour regression, we are unable to conclusively confirm that the tumour regression is due to the patient taking CBD oil.”

Cannabis has a long ‘medicinal’ history in modern medicine, having been first introduced in 1842 for its analgesic, sedative, anti-inflammatory, antispasmodic and anticonvulsant effects. And it is widely believed that cannabinoids can help people with chronic pain, anxiety and sleep disorders; cannabinoids are also used in palliative care, the authors add.

“More research is needed to identify the actual mechanism of action, administration pathways, safe dosages, its effects on different types of cancer and any potential adverse side effects when using cannabinoids,” they conclude.

Notes for editors
Please note: out of respect for patient confidentiality we don’t have the names or contact details of the cases reported in this journal.

Funding: None declared

Link to Academy of Medical Sciences labelling system
https://press.psprings.co.uk/ AMSlabels.pdf

Externally peer reviewed? Yes
Evidence type: Single case report
Subjects: People