CBD for Thyroid Disorders
In America, approximately 20 million people suffer from some kind of thyroid disorder, and close to 60 percent of the affected don’t know about their condition.
According to the American Thyroid Association 1 women are a lot more likely to experience thyroid problems than men. Doctors usually prescribe traditional medicines to people with thyroid problems.
However, the medicines may not always work. In fact, they could end up presenting quite a few side effects. People are, therefore, seeking refuge in alternative medicines. Many studies indicate CBD can be effective at treating an array of thyroid-related issues.
Found in the endocrine system, your thyroid gland is a vital organ. It’s a butterfly-shaped, small gland located below your voice box and in front of your neck. The gland produces and gives out two important hormones – T4 (tetraiodothyronine) and T3 (triiodothyronine) – that control your body’s metabolism and determine how your cells utilize energy.
Also, the gland manages the pace of several processes, which include heart rate and body temperature. Generally, body metabolism management is critical for regulating weight, mood, and physical and mental energy levels.
Moreover, the thyroid gland converts the food you ingest into energy so that your body keeps functioning properly. Several thyroid problems are due to an atypical secretion of thyroid hormones. However, all kinds of thyroid disorder/disease have unique causes, risks, and diagnoses. It’s worth noting that many studies are pointing at how CBD could be potentially beneficial in treating thyroid diseases.
CBD and the Endocannabinoid System and Their Direct Impact on the Thyroid Hormone Release
The human body’s ECS (endocannabinoid system) exerts its strong influence in different ways. For instance, it regulates poise within various processes, such as thyroid function. According to an article published by National Institute of Health (NIH) 2 , scientists have discovered that the thyroid gland’s cells have cannabinoid receptors on them.
Multiple regulations and restrictions have made it quite difficult for researchers to learn more about cannabinoids and what role they play in the treatment of a thyroid disorder. Even though human-based research on the matter isn’t extensive yet, a study 3 was carried out on animals in 2002. It discovered that CB1 receptors control thyroid hormone release.
Also, it was found cannabinoids administration had a say in thyroid hormonal activity. In 2015, another 4 was carried out by the NIH, which discovered cannabinoid receptors can theoretically be therapeutic targets for benign and malignant thyroid lesions.
Furthermore, a research study 5 carried out by the Journal of Endocrinology exhibited that endocannabinoid receptors are situated within the sections of the brain. The receptors transmit signals to the gland. This shows the likelihood of cannabinoids, such as CBD, influencing the thyroid gland’s performance and overall health.
Different thyroid disorders
A thyroid disorder is a condition that impacts the thyroid gland. Different kinds of thyroid disorders either affect the gland’s function or its structure. A disorder is usually linked to the glands either releasing excessive thyroid hormones (hyperthyroidism) or too little hormones (hypothyroidism). Other specific thyroid disorders are:
It’s a non-cancerous swelling of the gland, with the most common cause being an iodine-deficient diet. Goiter could affect people at any age, but it’s most common in people who are 40 years old or more. Other risk factors are certain medication usage, family medical history, radiation exposure, and pregnancy.
A thyroid nodule is a common endocrine complaint that doesn’t give out signs or symptoms. But when they do show symptoms, those include hyperthyroidism, pain at the nodule site that could move to the jaw or ear, difficulty swallowing or shortness of breath (in case of a large nodule), and rare instances of speaking difficulties or voice hoarseness complaints. Most thyroid nodules are not harmful. They become cancerous usually in males or in an aged person.
This cancer isn’t the most common form of cancer in general, but it certainly is common within the endocrine realm. DNA mutations occurring spontaneously or as a response to toxic substances or environmental exposure could modify regular thyroid cells. The hereditary alterations push the cells to reproduce their own selves rapidly without regular controls that are usually synonymous to the remaining parts of the gland. The real cause of this disease is unknown, or the risk factors are unclear.
What is hyperthyroidism?
Hyperthyroidism is a thyroid condition that indicates denotes an overactive thyroid gland. One out of every 100 women 6 could be suffering from this condition. It’s not common in men, however. Several conditions could cause hyperthyroidism, which includes excess iodine consumption, thyroid inflammation, tumors of the testes or ovaries, benign pituitary or thyroid gland tumors, and large quantities of tetraiodothyronine administered through medication or dietary supplements.
Grave’s disease is among the major causes of hyperthyroidism, found in approximately 70 percent of people with a hyperactive thyroid. It induces antibodies to push the thyroid into secreting too much hormone. Thyroid nodules could also cause the thyroid gland to produce its hormones in excess. This condition is called multinodular goiter or toxic nodular goiter. Increased thyroid hormone production could present the following symptoms:
- racing heart
- increased sweating
- trouble sleeping
- brittle nails and hair
- thin skin
- weight loss
- muscle weakness
- bulging eyes
CBD for Thyroid How CBD can help treat hyperthyroidism
Patients with hyperthyroidism usually report major or minor relief from negative symptoms of their disease. Regularly using CBD oil for thyroid helps individuals normalize their body weight, by putting an end to diarrhea issues and reestablishing their appetite. CBD for thyroid disorder gets rid of irritability and anxiety-related sleep disorders. Moreover, CBD for thyroid disorder helps with heart function regulation, the trembling of fingers and hands, and muscular aches, if any.
Does CBD affect thyroid medication?
There has been no clinical evidence showing interactions between CBD and thyroid medication such as Levothyroxine. A good way to get an idea if CBD will interact with your thyroid medication is to look for the “grapefruit warning” on the label.
More than 85 drugs 7 interact with grapefruit, however no thyroid medications are present on that list.
Nonetheless, we always recommend you read the label of your medication carefully and always consult with a doctor before taking CBD in combination with any medication.
What is hypothyroidism
Hypothyroidism is the reverse of hyperthyroidism. In this case, the thyroid gland is unable to produce enough hormones or is underactive. This disorder usually follows Hashimoto’s disease, the damage inflicted by radiation treatment, or thyroid gland removal surgery. While not all individuals with Hashimoto’s exhibit hypothyroid signs, thyroid antibodies could be the marker for thyroid diseases in the future.
Endocannabinoids and the Endocrine System in Health and Disease
Some of the earliest reports of the effects of cannabis consumption on humans were related to endocrine system changes. In this review, the effects of cannabinoids and the role of the CB1 cannabinoid receptor in the regulation of the following endocrine systems are discussed: the hypothalamic-pituitary-gonadal axis, prolactin and oxytocin, thyroid hormone and growth hormone, and the hypothalamic-pituitary-adrenal axis. Preclinical and human study results are presented.
Keywords: Corticosterone; Gonadotropin; Gonadotropin-releasing hormone; Growth hormone; HPA axis; Oxytocin; Prolactin; Testosterone; Thyroid hormone.
Luo Q, Chen S, Deng J, Shi L, Huang C, Cheng A, Liu W, Fang J, Tang L, Geng Y, Chen Z. Luo Q, et al. Metab Brain Dis. 2018 Oct;33(5):1483-1492. doi: 10.1007/s11011-018-0255-x. Epub 2018 Jun 11. Metab Brain Dis. 2018. PMID: 29948652
Van den Berghe G, Shalet SM. Van den Berghe G, et al. Novartis Found Symp. 2002;242:205-15; discussion 216-21. Novartis Found Symp. 2002. PMID: 11855689 Review.
Rettori V, De Laurentiis A, Fernandez-Solari J. Rettori V, et al. Exp Neurol. 2010 Jul;224(1):15-22. doi: 10.1016/j.expneurol.2010.03.019. Epub 2010 Mar 29. Exp Neurol. 2010. PMID: 20353777 Review.
Surkin PN, Gallino SL, Luce V, Correa F, Fernandez-Solari J, De Laurentiis A. Surkin PN, et al. Psychoneuroendocrinology. 2018 Jan;87:131-140. doi: 10.1016/j.psyneuen.2017.10.015. Epub 2017 Oct 18. Psychoneuroendocrinology. 2018. PMID: 29065362
Hillard CJ, Beatka M, Sarvaideo J. Hillard CJ, et al. Compr Physiol. 2016 Dec 6;7(1):1-15. doi: 10.1002/cphy.c160005. Compr Physiol. 2016. PMID: 28134998 Free PMC article. Review.
Cited by 6 articles
Fang Q, Zhang Y, Chen X, Li H, Cheng L, Zhu W, Zhang Z, Tang M, Liu W, Wang H, Wang T, Shen T, Chai R. Fang Q, et al. Front Bioeng Biotechnol. 2020 Jan 8;7:436. doi: 10.3389/fbioe.2019.00436. eCollection 2019. Front Bioeng Biotechnol. 2020. PMID: 31998703 Free PMC article.
Zuccarini G, D’Atri I, Cottone E, Mackie K, Shainer I, Gothilf Y, Provero P, Bovolin P, Merlo GR. Zuccarini G, et al. Int J Mol Sci. 2019 Dec 25;21(1):168. doi: 10.3390/ijms21010168. Int J Mol Sci. 2019. PMID: 31881740 Free PMC article.
Reed SC, Haney M, Manubay J, Campagna BR, Reed B, Foltin RW, Evans SM. Reed SC, et al. Pharmacol Biochem Behav. 2019 Jan;176:72-82. doi: 10.1016/j.pbb.2018.11.008. Epub 2018 Dec 4. Pharmacol Biochem Behav. 2019. PMID: 30521833 Free PMC article.
Bershad AK, Miller MA, Norman GJ, de Wit H. Bershad AK, et al. Horm Behav. 2018 Jun;102:41-47. doi: 10.1016/j.yhbeh.2018.04.009. Epub 2018 Apr 24. Horm Behav. 2018. PMID: 29673620 Free PMC article. Clinical Trial.
Thistle JE, Graubard BI, Braunlin M, Vesper H, Trabert B, Cook MB, McGlynn KA. Thistle JE, et al. Andrology. 2017 Jul;5(4):732-738. doi: 10.1111/andr.12358. Epub 2017 Apr 10. Andrology. 2017. PMID: 28395129 Free PMC article.