Safety and Efficacy of Cannabis in Tourette Syndrome
For many individuals with Tourette syndrome (TS), available medications do not help with their symptoms, or cause significant side effects. Two small controlled trials have investigated the effect of oral delta-9-tetrahydrocannabinol (THC), a principal psychoactive ingredient of cannabis, in TS patients. While these trials have shown promising results, the effect sizes were not as large and consistent as those reported by patients with regards to inhaled cannabis (smoked or vaporized). Indeed, based on anecdotal evidence, patients have much greater improvement in their symptoms using inhaled cannabis than using cannabinoid pharmaceuticals. However, there have been no controlled trials of inhaled medical cannabis for TS to date. Furthermore, various medical cannabis products are authorized in Canada with different contents of THC and cannabidiol (CBD), another primary cannabinoid. No data exists regarding the dosing, efficacy and safety of these products in the treatment of TS. To gather such data, a double-blind, randomized, crossover pilot trial will be conducted to compare the efficacy and safety of three vaporized medical cannabis products with different THC and CBD contents, as well as placebo, in adults with TS. As well, the PK/PD profile of THC and CBD of the products will be assessed and correlated with tic symptoms
CBD for Tourette’s
Tourette Syndrome, also commonly called Tourette’s Disorder, is one of three types of tic disorders. Tic disorders are characterized by involuntary movements and vocalizations (“tics”), and a tic disorder is diagnosed as one of the three types according to the type of tics present and the length of time they have been present. Tourette’s involves at least two motor tics and one vocal tic that occur for more than one year. Both motor and vocal tics can range from being very mild and not noticeable, such as blinking or sniffing, to being large and disruptive, such as jumping or shouting.
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Around ten percent of people with Tourette’s experience complex vocal tics such as swear words. Most Tourette’s cases involve mild tics and are easy to manage, but it can become more complicated as the complexity and scale of the tics increases. When tics interfere with an individual’s normal social functioning, such as at school or work, they may seek treatment or therapy. It’s preferred to use a treatment that does not cause side effects or is unlikely to cause side effects. Speech therapy and behavior modification therapy are two such available treatments, and some medications are also available. However, since these medications pose a risk of some undesirable side effects, many people have become interested in CBD as an alternative. More information in our guide down below.
Safety of Using CBD for Tourette’s
Using CBD for Tourette’s is very unlikely to cause any side effects, and the treatment has been studied for more than forty years with very positive results. If CBD appeals to you as a potential treatment for you or a loved one with Tourette’s, discuss this option with your doctor and use our list of the ten best products as a reference to find high-quality CBD.
Benefits: How Does CBD Oil Treat Tourette’s?
People who use CBD for Tourette’s experience a -+few main benefits that can greatly improve their quality of life and ability to function socially.
- Reduced frequency and severity of tics – The most obvious reason to use CBD for Tourette’s is to treat and reduce tics. Both motor and vocal tics can be reduced by using CBD, but the reduction of motor tics seems to be more significant. The greatest reduction is in the frequency of the tics, but the severity or “violence” of the tics may also be reduced. While the reason for this effect is not understood, it is well documented that it does happen, and some individuals even have tics disappear when they use CBD.
- Improved sleep – Tourette’s often interferes with a person’s quality of sleep, particularly if they experience severe tics during the night. CBD can improve the sleep of Tourette’s patients both by reducing tics and by making it easier to relax and sleep well. In fact, the use of CBD for sleep is common even among people without medical conditions. – Obsessive-compulsive disorder (OCD) often occurs alongside Tourette’s. The compulsions and intrusive thoughts that are characteristic of many OCD cases can be improved with the use of CBD, which has a positive effect on mental health in general.
- Improved emotional and mental state – People with Tourette’s, especially children with Tourette’s, often feel sudden anger or experience outbursts of aggression. CBD is, for many people, very soothing and helps to regulate mood. The aggression that occurs in Tourette’s can be greatly improved with CBD treatment.
How to Use CBD for Tourette’s Syndrome?
The type of CBD that should be used for Tourette’s depends on the patient’s:
- Age – The laws regarding cannabis use in minors are often different from those for adults, so depending on the age of the patient and the location you live in, there may be different restrictions. Adults may choose to use CBD products that also include THC, for example, which is often not an option for minors.
- Symptoms – The dosage may depend on the size of the individual as well as the severity of symptoms. Minor tics may disappear with a lower dose of CBD than what is required for more severe tics.
- Personal preferences – CBD oil, edibles, and vape are three common types of CBD products. They all take different amounts of time to take effect, last for different amounts of time, and give a different experience. People who dislike the taste of cannabis may prefer to avoid CBD oil, for example, which takes effect quickly but is used by placing it directly in the mouth. Edibles may be best for improving sleep, as they tend to have the longest-lasting effects.
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What to Consider When Buying Oil for Tourette’s?
Your CBD treatment for Tourette’s should be personalized to your tics and your experience, so there are some factors to consider to make the usage safe for you.
- Quality: In the United States, cannabis products are not regulated by the FDA, so there is no guarantee of the quality or even of the accuracy of the label. Third-party companies can perform testing to verify that a product is high-quality and free from contaminants. Choose a product from our top ten list or another tested product to ensure that it is safe to use.
- Type of cannabis: If you are an adult in an area that allows the use of THC, you may consider full-spectrum CBD products, which contain enough THC to have a psychoactive effect. Some people simply enjoy this effect, and some believe that cannabis compounds are more effective when used together, so THC and CBD may work best as a pair.
- Legality: Finally, you should consider the cannabis regulation laws in your area. CBD is legal in most states, but not all, and some countries around the world also do not allow its use. Make sure you know the laws that apply to you before buying any CBD products.
Tourette’s is a condition that can affect the social function, sleep, and emotional state of those affected by it to a severe degree. Natural and safe treatments like CBD can offer relief from symptoms and improve the lives of patients. It reduces tics, improves sleep quality, and improves the emotional state in many people who use it. Before starting CBD for Tourette’s, discuss the treatment with your doctor. They will be able to advise you on any potential interactions with other medications or conditions. When you have a safe treatment, plan laid out, use our ultimate guide and unbiased reviews of the best products to find an effective, high-quality option.
Treatment of Tourette syndrome with cannabinoids
Cannabinoids have been used for hundred of years for medical purposes. To day, the cannabinoid delta-9-tetrahydrocannabinol (THC) and the cannabis extract nabiximols are approved for the treatment of nausea, anorexia and spasticity, respectively. In Tourette syndrome (TS) several anecdotal reports provided evidence that marijuana might be effective not only in the suppression of tics, but also in the treatment of associated behavioural problems. At the present time there are only two controlled trials available investigating the effect of THC in the treatment of TS. Using both self and examiner rating scales, in both studies a significant tic reduction could be observed after treatment with THC compared to placebo, without causing significant adverse effects. Available data about the effect of THC on obsessive-compulsive symptoms are inconsistent. According to a recent Cochrane review on the efficacy of cannabinoids in TS, definite conclusions cannot be drawn, because longer trials including a larger number of patients are missing. Notwithstanding this appraisal, by many experts THC is recommended for the treatment of TS in adult patients, when first line treatments failed to improve the tics. In treatment resistant adult patients, therefore, treatment with THC should be taken into consideration.
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