Cbd oil spray dosage for sleep
There isn’t one dosage that will work for everyone, but there are general guidelines. T he U.S. Food and Drug Administration doesn’t have recommendations on how much to take, but e xperts generally recommend 1–6 mg per every 10 lbs of body weight. For example, if you weigh 100 lbs, you could take 10–60 mg daily. The chart below is a handy reference for how much you might start with. You can also use our CBD dosage calculator to quickly find your results.
|Weight and dosage||100 lbs||150 lbs||200 lbs||250 lbs||300 lbs|
|1 mg||10 mg||15 mg||20 mg||25 mg||30 mg|
|2 mg||20 mg||30 mg||40 mg||50 mg||60 mg|
|3 mg||30 mg||45 mg||60 mg||75 mg||90 mg|
|4 mg||40 mg||60 mg||80 mg||100 mg||120 mg|
|5 mg||50 mg||75 mg||100 mg||125 mg||150 mg|
|6 mg||60 mg||90 mg||120 mg||150 mg||180 mg|
CBD products are available in varying doses and sizes. Some products that appear to be large in size aren’t necessarily a large dose of CBD. Remember to check how many milligrams are in each serving.
How much you should take will depend on lots of factors, including your age, your sex, the reason you’re taking it, your metabolic rate (how quickly you metabolize compounds), and the quality of the product
If you’re taking CBD for a serious case of insomnia, or some other condition such as anxiety or depression, you may need to be in the higher range of recommended use. Speak to your doctor about how much you can start with, especially if you have any medical condition. CBD may interact with other drugs that you’re taking, so talk to your doctor to make sure there aren’t any drug interactions.
How to Calculate Dosage If Not Labeled
Capsules and gummies will tell you exactly how many milligrams of CBD are in each serving. With oils or sprays, it may or may not tell you how much CBD is in each drop or spray. If it doesn’t, then you have to do a little math.
Each drop is .05 mL, so if you have a 10 mL bottle, the bottle will contain 200 drops. You work this out by dividing the size of the bottle by the number of drops. If the bottle contains 500 mg of CBD, it will give you 2.5 mg of CBD per drop (500 mg divided by 200 drops). If you want to take 25 mg of CBD, you will take ten drops.
Increasing Your CBD Dosage
It’s a good idea to start slow. Begin on the lower end of the CBD dosage to make sure that you don’t have a negative reaction. CBD has been found to be generally safe, and occasionally users report appetite changes, fatigue, and diarrhea.
Keeping a record of how much you take and how you feel can also be helpful. If after a few days you aren’t feeling much effect, you can slowly increase your dosage. If you’re taking CBD to improve your sleep, track how long it took you to fall asleep, how many times you woke up during the night, how long you slept, and how you felt when you woke up.
One of the best ways to track your sleep is with a sleep app. I’ve tested out several, and my favorite is Sleep Cycle. Besides tracking a lot of basic information about your sleep, it has a great feature where you can add “sleep notes,” such as “30 mg CBD,” “40 mg CBD,” etc. Every night you can check off the relevant sleep note to mark what you did that day, and it will track how well you’re sleeping with each of the different notes. For example, I can see that when I eat a lot of sugar during the day, my sleep quality decreases by 15%. When I take 120 mg of CBD, my sleep quality increases by 20%. When I take 50 mg of CBD, my sleep quality increases by 10%.
It also takes people different amounts of time to experience the effects. There are many reported benefits of CBD, such as pain relief, stress relief, being able to fall asleep faster and sleep deeper, but one of the most common effects of CBD is a sense of calm. Some may feel it within an hour; for some, it may take a few days or even a few weeks. If you don’t notice anything after a week, increase your dose. If you are pretty sensitive to supplements, you may increase the dose every few days until you start noticing benefits. There are no guarantees that you will feel anything different, but you have to give it time.
Another factor is how often you take CBD. Instead of taking your daily intake in one dose, experiment by dividing it in two and taking it twice per day to see if you feel more benefits. As CBD stays in your system for 4–6 hours, you may find it helpful to take it two or more times per day.
What Are the Best Ways to Take CBD?
There are a lot of ways to take CBD, including capsules, tincture, spray, added to a drink, creams, lotions, candy, and in a vape.
If you want to know exactly how many milligrams (CBD dosage) you’re taking, the best way is the capsule (or a gummy) as the bottle will tell you exactly how much is in each capsule. If you’re using a tincture, it’s more difficult to get the exact dose you’re looking for. Another benefit of capsules is that there’s no taste. With tinctures, you can taste more, and the flavor isn’t always great.
The fastest way to feel the effects is to use a tincture or spray. Place the CBD under your tongue and let the mucous membranes in your mouth absorb it for 60 to 90 seconds. Many people will feel the effects in around 20 minutes. If you take it in a capsule, or if you swallow a CBD liquid, it has to pass through your digestive system and be metabolized by your liver, so it could take an hour or two. Using CBD topically is better for dealing with chronic pain in a specific area.
Speed isn’t necessarily the most important factor in choosing how to take CBD. For some people adding it to their drink or smoothie is the most convenient, and for others, a capsule is best. No matter which way you choose, it’s a good idea to time it for the best effect. If you’re taking it to sleep better, you may want to take a capsule a couple of hours before bed, or a tincture 20 minutes before bedtime.
Make sure that you’re taking a high-quality CBD product. If you’re not, it will reduce the chances of you experiencing the benefits, and in rare cases, could cause you harm. Hemp is a bioremediator, meaning that it can extract toxins out of the soil. It was used by farmers in Chernobyl after the nuclear accident to help clean the soil.
High-quality brands will include a certificate of analysis (COA) that shows all of the third-party testing that has been done on the product to make sure that it’s free of toxins and other contaminants.
Can CBD Help You Sleep Better?
There’s a lot of research being done right now on insomnia and CBD, and the results so far are positive. Research published in the National Institutes of Health (NIH) found that when 160 mg of CBD was administered to subjects, they reported sleeping significantly more than those who took a placebo. Another study in the Journal of Pharmacology found that CBD increased sleep time in rats. Yet CBD administered during the day increased the amount of time to fall asleep, suggesting that CBD can make you more awake during the day.
It’s no surprise that CBD can help you get to sleep faster, stay asleep, and get more restful sleep as there are many conditions that CBD is reported to benefit, including, anxiety, depression, joint pain, COPD, diabetes, heart disease, and substance abuse.
Many researchers believe that there’s a connection between CBD’s benefits for reducing anxiety and increasing sleep.
There’s a lot of research being done on CBD as it’s become popular since the Farm Bill was passed. In 2018 the United States Food and Drug Administration (FDA) approved the first CBD-based treatment to help control epileptic seizures in Lennox-Gastaut syndrome and Dravet syndrome. There may be more CBD-based products approved by the FDA in the future.
Does CBD Make You High?
THC ( tetrahydrocannabinol)is the compound in marijuana that makes people high. Though CBD and THC come from the same plant, CBD doesn’t cause a person to get high. Some CBD products have trace amounts of THC (3% or less), but research from the Netherlands suggests that CBD can counteract some of the effects of THC. Some marijuana growers have even developed strains containing higher levels of CBD that make for a much milder high.
Will You Fail a Drug Test?
As CBD won’t make you high, it won’t cause you to fail a drug test. THC can affect a person’s mood, coordination, time perception, concentration, and memory, and even cause hallucinations. Occasionally THC can cause negative side effects including anxiety, rapid heart rate, and short-term memory recall issues. CBD doesn’t have the compounds that cause these effects.
If someone was taking a large amount of CBD, over 1,000 mg per day, they could trigger a false positive on a drug test. Most people take between 100 mg and 200 mg per day.
There are few known side effects of taking CBD. Those who do experience negative effects will have changes in appetite, fatigue, or diarrhea.
CBD can interact with other pharmaceuticals, so if you plan on using it, speak to your doctor. CBD can interact with any drug metabolized by cytochrome P450 enzymes, which can include:
- immune modulators
- angiotensin II blockers
- oral hypoglycemic agents
- HMG CoA reductase inhibitors
- calcium channel blockers
- HIV antivirals
Is CBD Addictive?
According to the National Institute on Drug Abuse, CBD isn’t addictive, and when someone stops using it, there are no withdrawal symptoms.
How CBD Works
CBD prevents the stress response that starts in the brain by activating the adenosine receptor in our endocannabinoid system, which controls the physiological response to stress called the hypothalamic-pituitary-adrenal axis (HPA). This process starts when the brain perceives something that it believes could cause us harm.
The first part of the chain is the amygdala, which contributes to emotional processing. The amygdala signals the hypothalamus which then signals the adrenals and the rest of the body. The adrenal glands send adrenaline into the body to make the heart beat faster, the muscles and organs receive more blood and oxygen, the brain receives more oxygen, and glucose and fat are released into the bloodstream. The person is now able to run faster or fight harder as they have more energy and are more aware.
When someone has chronic, low-level stress, they’re unable to sleep because this stress response is preparing them to run and/or fight, not sleep. Researchers believe that this may be the main way that CBD helps insomniacs get to sleep, by reducing or shutting off the HPA stress response.
How to Store CBD
Like many other oils, CBD can break down when exposed to heat, oxygen, or light, hence many CBD products are in dark brown or colored containers. The best place to store your CBD products is in a cool and dark place (a refrigerator is a good option). If you don’t expose your CBD products to heat, oxygen, or light, most products will last up to a year.
CBD Dosage Frequently Asked Questions
Here are the answers to the most frequently asked questions we receive about CBD dosage.
The U.S. FDA doesn’t have recommendations on how much to take, but experts generally recommend 1-6 mg per every 10 lbs of body weight. If you weigh 100 lbs, you could then take 10-60 mg daily.
Start with a low dose to make sure that you don’t have any negative reactions. If after a few days you aren’t feeling much effect, you can slowly increase your dosage.
If you want to know exactly how many milligrams of CBD you’re taking, capsules are the best. If you want to experience the effects the fastest, using a spray or tincture is best.
Research published in the National Institutes of Health (NIH) found that when 160 mg of CBD was administered to subjects, they reported sleeping significantly more than those who took a placebo.
THC is the compound in marijuana that makes people high. Though some CBD products have trace amounts of THC (3% or less), CBD counteracts the effects of THC. And CBD oils without THC are also available.
If someone was taking a large amount of CBD, over 1,000 mg per day, they could trigger a false positive on a drug test. Most people take between 100 mg and 200 mg per day.
According to the National Institute on Drug Abuse, CBD isn’t addictive, doesn’t cause a high, and when someone stops using it, there are no withdrawal symptoms.
CBD prevents stress that starts in the brain via the adenosine receptor in our endocannabinoid system, which controls the response to stress called the hypothalamic-pituitary-adrenal axis (HPA).
Can CBD help you sleep? Experts explain the current CBD research
This article was medically reviewed by Mia Hazle, MD, a psychiatrist in the Division of Addiction Psychiatry at Beth Israel Deaconess Medical Center.
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- CBD for sleep has limited research — though some early studies have shown promising results.
- But CBD researchers theorize that CBD may help with sleep by alleviating anxiety and pain.
- If you want to try it, doctors suggest taking 25 mg before bed, and increasing as you see fit.
Touted to relieve everything from acne and anxiety to pain and poor sleep, CBD (cannabidiol) is making waves in the wellness industry despite a lack of scientific evidence proving the compound’s overall effectiveness.
Medical term: CBD is a component of cannabis that does not cause you to feel high or stoned.
That said, a handful of small, preliminary studies have found that CBD may help improve the sleep quality of certain individuals. Here’s what researchers know so far.
Can CBD help you sleep?
There have only been a handful of small, trusted studies that look at pure CBD for sleep, says Jeff Chen, MD, MBA, Founder of the UCLA Cannabis Research Initiative and Cofounder and CEO of Radicle Science.
What the research says
of 72 adults with anxiety and sleep troubles found that doses of CBD ranging from 25 milligrams to 75 milligrams improved sleep in 66.7% of participants. found that since CBD can reduce pain, it may improve sleep in people who suffer from chronic pain and related sleep problems.
- A 2018 study of 27 healthy participants found that a dose of 300 milligrams of CBD had no significant effect on sleep versus a placebo.
Though early results are encouraging, researchers aren’t sure why CBD may help with sleep — but it may have something to do with how it can help improve underlying conditions.
“Sleep disorders, mood disorders, and pain disorders are often co-occurring, and CBD could possibly indirectly improve sleep by improving an underlying anxiety or pain condition,” says Chen.
And to make things even more confusing, it’s possible that smaller doses of CBD may have a stimulating effect rather than a sedating effect, says Me Fuimaono-Poe, MSN, FNP, faculty at Pacific College of Health and Science, and the medical director for the Malie Cannabis Clinic.
For example, a 2014 study found that a dose of 15 milligrams of CBD may have an “alerting” effect.
The lack of large-scale clinical studies makes it difficult to draw solid conclusions. “There is no firm evidence regarding whether CBD may help with sleep, and if so, what dose of CBD is most appropriate,” says Chen.
How should I take CBD to sleep?
Since researchers haven’t determined a rule of thumb when it comes to CBD dosage for sleep, experts can only guesstimate. If you want to give CBD a shot, Fuimaono-Poe suggests starting with 25 milligrams and increasing as needed, taken one to two hours before bed.
There’s also the question of what form of CBD is best for sleep. Fuimaono-Poe says two common delivery methods are taking CBD oil or smoking CBD flower. CBD oil is preferable and healthier for your throat and lungs since smoking can cause throat irritation and coughing, says Fuimaono-Poe.
However, smoking CBD flower comes along with the benefit of having a more rapid onset than taking a dose of CBD oil, so you can use that closer to bedtime. You’ll feel the effects five to ten minutes after smoking, says Fuimaono-Poe.
Risks of CBD
CBD is typically well-tolerated, however, it is possible to experience some side effects. Some documented potential side effects of CBD (discovered during human studies of using CBD for epilepsy and psychiatric disorders) include:
- Drug interactions
Additionally, there are some groups of people who should avoid using CBD, such as:
- Women who are trying to get pregnant, women who are pregnant, and women who are breastfeeding: Chen says researchers don’t know the impact of CBD on human fetuses or babies, but animal studies indicate that it stunts fetal development. Therefore, it’s safer to err on the side of caution and avoid CBD.
- People with liver disease or people who drink heavily: It’s possible that CBD may damage the liver, Chen says, so it may be safer for these people to not take CBD. This is because drinking excessive alcohol also causes damage to the liver.
- People taking certain medications: CBD may cause drug interactions or increase your risk of adverse side effects, says Chen. Therefore, if you take any prescription drugs, check with your doctor before taking CBD.
At the end of the day, more research is needed to determine the efficacy of CBD for sleep, as well as the best dosage and most effective ways to consume it.
However, in the meantime, it likely won’t hurt to give CBD a try if you’re experiencing trouble with sleep.
If CBD doesn’t help and your sleep problems persist or worsen, be sure to see a doctor for guidance.
Ashley Laderer is a freelance writer from New York who specializes in health and wellness. Follow her on Twitter @ashladerer
CBD Dosage: How Much Should You Take?
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Table of Contents
- Determining the Best CBD Dosage for You
- How to Calculate CBD Dosage
- How to Take CBD
Cannabidiol (CBD) is growing increasingly popular, thanks to its many purported health benefits and non-intoxicating properties (most CBD products contain less than 0.3% tetrahydrocannabinol, or THC). In fact, 60% of U.S. adults have tried CBD at some point and believe it has medicinal benefits, according to a recent Forbes Health survey of 2,000 U.S. adults conducted by OnePoll. As research evolves and sheds light on CBD’s efficacy, especially for pain relief, more and more people are adding it to their daily wellness regimens.
Consumers can choose from a variety of CBD products, from oils to gummies to vapes to capsules. But figuring out the safe and effective CBD dose for an individual is a complex decision.
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Here’s how to find the right CBD dosage for you and how to consume it safely.
Determining the Best CBD Dosage for You
With the exception of one CBD product, a prescription drug used to treat seizures associated with particular syndromes, the Food and Drug Administration (FDA) doesn’t regulate the use of CBD. (In fact, it’s illegal to market CBD as a supplement or add it to food.) Therefore, it’s best to consult a doctor with experience in CBD administration to determine your ideal dosage.
Expressed in milligrams (mg), CBD dosage largely depends on the conditions and symptoms you’re trying to treat and your unique endocannabinoid system, which is associated with motor control, behavior, emotions, the nervous system and homeostasis. CBD dosage remains an area of active research—more large, high-quality studies are needed in different populations to determine appropriate dosing, efficacy and safety guidelines.
“It’s best to start small and gradually increase your dose up to a level that gives you the desired effect,” says Cheryl Bugailiskis, M.D., a cannabis specialist at Heally, a telehealth platform for alternative medicine. Your starting point might look like half a CBD gummy or a drop of oil. Ideally, navigate this process under the guidance of a qualified physician.
If you’re still not sure where to start, mydosage.com offers a questionnaire and CBD calculator to help you based on your specific symptoms and usage goals.
How to Calculate CBD Dosage
When you consume CBD gummies, capsules or softgels, dosage is typically expressed per unit. For example, there may be 50 milligrams of CBD in each individual gummy. These products don’t offer much dosage flexibility since you can’t split up capsules easily. For instance, if one softgel capsule didn’t provide your desired result, you would have to take another full capsule, doubling the total dose.
CBD oil, on the other hand, makes it easier, to begin with a small dose. But calculating CBD oil dosage can be less straightforward. Oils and tinctures tend to come in a dropper bottle and, typically, only the total liquid volume and CBD contents are listed on the label. For example, the label might simply state there’s 1,500 milligrams of CBD in the 30-milliliter bottle.
But what does 1 milliliter look like? Due to the current lack of regulation of CBD, this calculation can be tricky. Start by figuring out the volume of a single drop in your dropper, which is usually 0.05 milliliters, according to Dr. Bugailiskis. If you’re unsure, ask the company.
Here’s where math comes in. Let’s continue with the 30-milliliter bottle with 1,500 milligrams of CBD and 0.05 milliliters in a single drop as our example.
1500mg÷30mL = 50 mg/mL
This bottle contains 50 milligrams of CBD per milliliter. Let’s see how many milligrams are in a drop:
50mg/mL ×0.05mL/drop = 2.5mg/drop
Each drop contains 2.5 milligrams of CBD.
Next, you can calculate how many drops you need to reach your goal dosage. Let’s say you want to consume 25 milligrams each day.
25mg÷2.5mg/drop = 10 drops
10 drops ×2.5mg = 0.5mL
With this CBD oil dosage calculator as your guide, you would find that you needed to consume 10 drops, or 0.5 milliliters, to reach 25 milligrams. And if you intend to consume 25 milligrams daily, you can expect this particular bottle to serve as a 60-day supply.
Some CBD products do some of this math for you and illustrate how many milligrams are in a milliliter, some even marking these points on the dropper so you know exactly what you’re taking.
CBD Dosage for Different Ailments
Without FDA approval, there is little guidance in the U.S. on how much CBD a person should consume for various conditions.
In many medical studies on CBD, you see administered doses reach hundreds of milligrams a day, which sounds severe compared to our starting dosage example of 25 milligrams. However, Steven Phan, founder of Come Back Daily, a CBD dispensary in New York, points out that patients in these studies are often dealing with serious flare-ups and pain-inducing conditions compared to everyday dispensary customers.
Below are clinically-studied CBD dosages based on different ailments and conditions. Note: Some of the formulations studied contained THC as well—not all available dosage research sticks strictly to CBD.
*Dosages are based solely on small, short-term clinical study results where CBD proved significantly successful over placebo. Much larger studies are needed to further strengthen the evidence.
FDA-approved Epidiolex administers CBD orally as a liquid to treat seizures associated with Lennox-Gastaut syndrome, Dravet syndrome and tuberous sclerosis complex. The dosage of Epidiolex is determined by taking the patient’s weight in kilograms (kg) into account.
Several countries, including Canada and those in the U.K., have approved the use of Sativex, an oral spray with equal amounts of CBD and THC, to treat pain stemming from multiple sclerosis. Canada has also approved it for treatment of cancer pain.
The medical and research community still has a long way to go before figuring out what dose works best for each condition. At an individual level, consumers can experiment with caution until they find what works best for them.
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How to Take CBD
Popular ways to take CBD include:
- Oils and tinctures (extracts of plant material dissolved in ethanol): A liquid that comes in a bottle with a dropper
- Gummies: A soft, chewable candy that’s often fruit-flavored
- Sprays: A liquid that comes in a bottle with a nozzle for spraying into the mouth
- Capsules: Tablets or softgels that are ingested by mouth
- Vapes: CBD oil that’s heated without ignition, resulting in an inhalable vapor
- Flower: Dried hemp plant that’s often ignited and smoked
- Edibles: Any food that CBD oil has been added to, such as brownies or chips
- Drinks: Any beverage that’s infused with CBD, often in the form of hemp extract
Your CBD product of choice will largely depend on your personal preferences, as well as your budget since prices vary depending on the potency of ingredients and manufacturing processes. Different mediums also offer varying levels of bioavailability—or how much of what you take is actually absorbed into your bloodstream to have an effect. For example, if you ingest 10 milligrams of CBD via 1 milliliter of liquid, your body might absorb about 60% of it, or about 6 milligrams.
Cannabinoids generally have a low bioavailability compared to other substances, according to Jordan Tishler, M.D., a physician specializing in cannabis treatment in Massachusetts. However, “products that contain emulsifiers like egg yolk (brownies) or lecithin (some gummies) do better,” he says.
With that said, ingesting CBD via gummies or other edibles may take longer to take effect since the CBD has to travel to your digestive system to be broken down and absorbed.
Can You Take Too Much CBD?
Like with any substance, you can take more CBD than your body can handle. Studies show doses up to 1,500 milligrams a day have been well-tolerated, but every person is different  Bergamaschi MM, Costa Queiroz RH, Zuardi AW, Crippa JAS. Safety and side effects of cannabidiol, a Cannabis sativa constituent. Current Drug Safety. 2011;6(4):237-49. . Ingesting too much CBD can cause unpleasant side effects, such as dry mouth, nausea, diarrhea, upset stomach, drowsiness, lightheadedness and general disorientation. While rare, liver damage can also occur.
What’s more, CBD can have serious interactions with certain medications. In evaluating available information on five prescription CBD-based medications, researchers found 139 medications could have a potential drug-drug interaction with CBD  Kocis PT, Vrana KE. Delta-9-Tetrahydrocannabinol and Cannabidiol Drug-Drug Interactions. Medical Cannabis and Cannabinoids. 2020;3:61–73. . People who take certain blood thinners, heart rhythm medications, thyroid medications and seizure medications need to be particularly careful.
At the end of the day, not all supplements are created equal, which is why it’s important to work alongside a health care provider when adding CBD to your wellness regimen and research reliable brands. And while emerging research and anecdotal evidence is promising, more large, randomized-controlled trials are needed to further understand the benefits of CBD and its dosing.