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How much cbd oil to take for osteoporosis

CBD for Osteoporosis: Can Hemp Oil Help Reverse Bone Loss?

Exciting new research has been exploring CBD’s powerful ability to speed fracture healing and preserve bone density.

Learn how it works and how to use CBD products for osteoporosis effectively.

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Estimates suggest more than 200 million people have osteoporosis around the world [1].

According to the International Osteoporosis Foundation, osteoporosis is responsible for a staggering 8.9 million bone fractures annually — meaning there’s an osteoporotic fracture roughly every three seconds [2].

Often referred to as a “silent disease,” many people don’t realize they have the condition until a fracture occurs.

Here, we will discuss osteoporosis, current treatment options, and scientific research on how CBD can help.


Updated on June 05, 2021

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How Does CBD Help With Osteoporosis?

CBD (cannabidiol) is the primary non-psychoactive compound in cannabis. It’s been shown to support bone metabolism indirectly through its effects on the endocannabinoid system (ECS).

The ECS is a complex network of receptors that work to regulate various aspects of our health — including the formation and degeneration of bone [3]. Through this system, CBD is thought to help reduce bone loss and promote the regeneration of lost bone tissue.

CBD should always be used in combination with other therapies for maximum benefit. CBD is not a cure for osteoporosis, but can offer a powerful supportive role when used alongside other medications, supplements, and exercises.

The benefits of CBD oil for osteoporosis may include:

  • May improve the density of bones
  • Alleviates pain & inflammation
  • Supports hormone balance
  • Relieves pain from bone fractures

1. CBD May Improve Bone Density

Research has discovered that CBD appears to enhance the growth and strengthening of bones through accelerated osteoblast formation.

Researchers believe that osteoclasts — the cells that breakdown bone — have a cell receptor that, when activated, speeds up bone loss and degeneration. This receptor is known as GPR55. CBD has been shown to specifically block the activation of this receptor, reducing osteoclast activity [5].

Further, in a recent study in Israel, mice were given CBD or a combination of THC and CBD. The study found that the administration of CBD alone has significant effects on fracture healing with increased bone strength and toughness by stimulating Lysyl Hydroxylase — an enzyme involved in bone healing [5].

This research has given us a deeper insight into how CBD influences the body and opens up some exciting potential for further research.

2. CBD Alleviates Pain & Inflammation

CBD may have a therapeutic role in inflammation and healing. It has long been used by people with chronic pain and offers a non-habit-forming alternative to pain medications.

Many patients have reported replacing their prescription pain medications with CBD, with evidence that its use can help in the treatment of headaches, mental health disorders, insomnia, arthritis, and other chronic pain syndromes [6].

What’s The Dose of CBD Oil For Osteoporosis?

The key is to start low and go slow.

As yet, there are no standardized dosing guidelines for CBD use. CBD oil can come in many different strengths. As products vary greatly, it’s important to read the label of the specific product you are using.

When it comes to managing osteoporosis, the benefits will take several months before any change is noticed. We recommend starting with a moderate dosage (based on your weight using our CBD oil calculator below).

If you experience side-effects (more on this later), reduce the dose until they disappear.

CBD Oil Dosage Calculator

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Is CBD Oil Safe?

CBD is safe, even at high doses — but there are a few exceptions to be aware of.

According to the WHO, CBD oil, in its pure state, does not cause harm or have the potential for abuse — even at high doses [7].

If you’re using any prescription medications, or have underlying health issues, you should always speak with your doctor before taking CBD. Certain medications may interact with CBD and lead to side-effects.

What is Osteoporosis?

Osteoporosis means “porous bones.” It results in fragile bones. The weakness of the bones puts those affected at a higher risk of fractures.

As the bones become thinner, even a minor fall or bump can cause a serious injury.

Middle-aged women are at the highest risk — however, men are also affected.

The main concern most people have when talking about osteoporosis is the high risk of bone fracture. A fracture is a complete or partial break in a bone.

It’s estimated that 50% of women and 20% of men over the age of 50 will have an osteoporosis-related fracture in their lifetime [1].

With osteoporosis, the most common bones affected are the hip, wrists, and spine. Fractures and breaks can lead to chronic pain and mobility issues.

Understanding the Definitions
  1. Cortical bone — the hard outside layer of all bones and makes up most of your skull and ribs.
  2. Spongy bone — occurs inside the vertebrae and the ends of the long bones, such as the thigh bones.
  3. Osteoblasts — specialized cells involved in producing new bones.
  4. Osteoclasts — specialized cells involved in breaking down bones.
  5. Bone density — the amount of mineral content in a bone.

Symptoms of Osteoporosis

There are no specific symptoms of osteoporosis — the first sign is usually a bone fracture. There are other symptoms, but these can be difficult to identify.

Other signs and symptoms may include:

  • Back pain
  • Collapsed or fractured vertebra
  • Loss of height
  • Stooped posture
  • Lowered grip strength

Menopause & Osteoporosis

In osteoporosis, there is a thinning of the cortical bone and reduced bone density and structure in the spongy bone. Menopause is one of the main causes of the condition.

Bone tissue is continuously broken down and replenished. It’s a regular cycle, fluctuating on both a daily and monthly basis — affected by things such as time of day, diet, and season.

Specialist cells within the bones called osteoblasts and osteoclasts are essential for these fluctuations in healthy bones. From birth to adolescence, more bone is formed than broken down.

By the end of adolescence, bone growth has completed. By your mid to late 20s, peak bone mass has been achieved.

The sex hormones estrogen and testosterone have a major role in maintaining healthy bones in both men and women.

In menopause, as estrogen levels drop, the balance of hormones that were working to control bone density begins to fall apart. The result is an acceleration in bone loss. Women can lose up to 10% of their total bone mass within the first five years of menopause.

Risk Factors for Osteoporosis

  1. A family history of osteoporosis
  2. Previous bone fractures
  3. Age — people over 50 are at the highest risk
  4. Early menopause — before the age of 45
  5. Weight — being overweight is a major risk factor
  6. Vitamin D — important in the maintenance of bone tissue
  7. Calcium intake — calcium is a key mineral in bone architecture
  8. Lack of exercise — weight-bearing exercises directly lower the risk of osteoporosis
  9. Smoking (linked with osteoporosis)
  10. Alcohol intake — over three standard drinks per day increases the risk of osteoporosis [1]
  11. Medications — such as corticosteroid use
  12. Medical conditions — such as thyroid problems, celiac disease, chronic liver disease, kidney disease, or rheumatoid arthritis
  13. Conditions that affect the absorption of nutrients — such as Crohn’s disease, celiac disease, and other inflammatory bowel conditions

Diagnosing Osteoporosis

If osteoporosis is suspected, your doctor will most likely send you for a bone density scan.

This scan is used to measure bone mineral density (BMD). It is usually performed using a dual-energy x-ray absorptiometry (DEXA). This is a non-invasive process where, for 10 to 15 minutes, a machine passes over your body while you lie flat on a table.

The bone density scan will give you a T-Score and Z-Score, used to determine your risk of developing a fracture and whether further tests are needed.

According to the World Health Organization (WHO), your T-Score is classed as follows:

  • -1.0 or above is normal bone density.
  • Between -1.0 and -2.5 means you have low bone density or osteopenia.
  • -2.5 or below is a diagnosis of osteoporosis.

The following procedures can also be performed to determine bone injury or fractures as a result of osteoporosis:

1. Bone X-Ray

Bone x-rays produce images of bones that aid in the diagnosis of fractured bones, which are sometimes a result of osteoporosis.

2. CT Scan

CT scans of the spine are used to assess alignment and fractures. They can be used to measure bone density and determine whether vertebral fractures are likely to occur.

3. Magnetic Resonance Imaging (MRI)

An MRI of the spine is used to evaluate vertebral fractures for evidence of underlying diseases, such as cancer, and to assess the newness of the fracture.

How is Osteoporosis Treated?

Depending on how severe your osteoporosis is and your risk of bone fracture, your doctor may recommend lifestyle changes to strengthen your bones.

Lifestyle changes can help to ensure both men and women take steps to prevent the risk of developing osteoporosis.

1. Lifestyle & Diet Changes
  1. Incorporate a varied diet with plenty of fresh fruit, vegetables, and whole grains
  2. Avoid smoking
  3. Reducing alcohol intake
  4. Limit caffeine
  5. Do regular weight-bearing and strength-training activities
  6. Ensure adequate vitamin D and calcium intake

However, if your osteoporosis is more advanced, lifestyle changes alone may not be enough to help you strengthen your bones.

Prescription medications are standard care in the treatment of established osteoporosis. Their purpose is to either increase the formation of new bone or slow down the breakdown process.

However, they each come with their own set of side-effects and risks.

2. Bisphosphonate Medications

Bisphosphonates encourage bone density by slowing the breakdown of cells. You can take them with a combination of vitamin D and calcium supplements.

Side-Effects of Bisphosphonates:

3. Selective Estrogen Receptor Modulators (SERMs)

SERMs mimic estrogen in the body, reducing bone loss and increasing bone formation.

Side-Effects of SERMs:

4. Denosumab

This is given via an injection under the skin twice a year. It slows down the breakdown of bone, resulting in higher bone mineral density and reduced fractures. It is often used as an alternative to bisphosphonates.

Side-Effects of Denosumab:

5. Hormone Replacement Therapy (HRT)

Doctors prescribe HRT for women during menopause when there is a drop in estrogen levels, increasing the risk of osteoporosis. However, HRT is no longer routinely recommended due to the increased risks with long-term use.

Side-Effects of HRT:

6. Testosterone Therapy

When testosterone levels are low in men, doses of testosterone are given by injection to improve bone density.

Side-Effects of Testosterone Therapy:

  • Acne and oily skin
  • Worsening of sleep apnea
  • Increased risk of blood clots
  • Increased risk of prostate abnormalities
  • Enlarged breasts in men
  • Decreased testicular tissue
  • Increased aggression, mood swings
  • Increased risk of heart disease and stroke (maybe)

Final Verdict: Using CBD for Osteoporosis

Osteoporosis can be a debilitating disease, and the fear of bone fracture can have a significant effect on one’s lifestyle and mobility.

While there is no cure, there is good evidence that CBD may be an effective treatment for osteoporosis by slowing down the progression of the disease and relieving pain.

These are very exciting times, especially as we look at CBD and the clinical research that’s still in its infancy regarding verifying its use in reducing bone loss and fracture.

Based on this information, CBD is seen as a safe, effective, all-natural therapeutic treatment for osteoporosis.

CBD Oil for Osteoporosis – Benefits and Options

In a person with osteoporosis , the bone structure is compromised- the integrity of the bones is weakened and bone formation is affected.

Osteoporosis is one of the most common bone diseases seen in human beings. It is characterized by a decrease in bone density that leads to fragile and weaker bones. This weakening results in higher risks of bone fracture that is most often seen in the wrist and hip regions or spine collapses.

There are a number of medically approved ways to treat osteoporosis .

The most widely used drugs used to treat osteoporosis are called bisphosphonates. These are generally made available in the form of:

  • Fosamax (alendronate)
  • Boniva (ibandronate)
  • Actonel (risedronate).

However, with research studies and the latest medical advancements, it is seen that medical marijuana is especially beneficial for pain relief . Concerning osteoporosis , research shows that CBD oil can beneficial in treating the symptoms of this bone disease .

The studies show that CBD extract acts as a natural remedy to improve bone health. Also, CBD oil and other CBD products were found to improve the health of bone tissues, bone mass , and bone density of the weakened bone , promoting active living.

CBD is one of the many cannabinoids (compounds) found in the cannabis plant . It is referred to as cannabis plants as either marijuana or hemp, based on the THC content they contain. Recent studies have shown that it can be used for therapeutic purposes.

CBD Oil for Osteoporosis : Hemp Oil for Bone Loss

The two primary compounds in the cannabis or marijuana plant are THC and CBD , which have varying effects on the consumer. Unlike THC, CBD is not a psychoactive compound. It does not change the consumer’s state of mind when used.

CBD may produce significant changes in the body, and it also shows some important medical benefits. Research studies have shown that CBD extract makes bones stronger while healing them by promoting collagenous matrix maturation.

This, in turn, enhances bone mineralization. After the bones are treated using CBD , they begin to break. Thus, topical CBD like cannabis oil improves overall bone health and bone density .

Cannabis oil is also capable of easing chronic pain or joint pain . There is also growing evidence that cannabis oil can ease the effects of osteoporosis , including bone formation , loss of bone mass , formation of bone tissue , decrease in bone loss , etc., bringing this bone disease to a manageable level. The cannabinoid is capable of reducing the risk of bone fracture .

A cannabinoid produces effects in the body by interacting with cannabinoid receptors. This forms a part of the endocannabinoid system . The body has two cannabinoid receptors:

  • CB1 cannabinoid receptors: These are present throughout the body, specifically in the brain. They coordinate movement, emotion, mood, pain , appetite, thinking, memories, etc.
  • CB2 cannabinoid receptors: The CB2 receptors are typical in the immune system. These impact chronic pain and inflammation.

THC intertwines to CB1 receptors, but CBD stimulates the receptors so that the body produces cannabinoids on its own. These are known as endocannabinoids. This type of cannabinoid receptor is needed for the regulation of bone metabolism .

Physiologically, it is essential to maintain a balance between osteoclasts and osteoblasts for optimum bone health . As you get older this delicate balance is impaired and you have an increased risk of bone fracture and bone loss .

CBD Dosage for O steoporosis :

Many studies state that professionals are yet to determine the most effective therapeutic dose of hemp oil for osteoporosis . A lot about hemp oil is still unknown, and hence its exact dosage or effectiveness cannot be determined.

Professionals agree that hemp oil or CBD oil certainly provides therapeutic benefits for patients suffering from chronic pain and other bone diseases. The exact dosage for treating a particular condition cannot be determined.

Despite the lack of knowledge about the accurate dosage, patients who have been prescribed a CBD product like hemp seed oil should consult with their doctor regarding an estimate of seed oil for treatment. Doses generally range from as low as 5mg per day to about 100mg per day. Your bone mass and overall health play an important role in determining the dosage size.

How to Take CBD Oil for Osteoporosis?

There is plenty of evidence suggesting hemp oil which is a derivate of the cannabis plant , is a restorative treatment for osteoporosis .

Human research trials are still needed to verify the effects of hemp seed oil for osteoporosis ; however, there is a promising future for treating medical challenges and osteoporosis in humans. Human clinical trials involving CBD oil , CBD cream , CBD vape oils , and topical CBD products for bone diseases are underway.

CBD treats pain and adverse effects caused by high blood pressure and neuropathy in people coping with dormant symptoms of anxiety and depression. Hemp plant also has improved the mental health of people living with mental health illnesses-hemp seed has enabled people to manage anxiety and depression.

Given the physical effects of arthritis pain and the debilitating effects of osteoporosis, it is likely that osteoporosis patients also suffer from anxiety or depression. There is enough evidence to believe that optimal amounts of bOHVYF highlight–related-topic”>CBD bOHVYF highlight–related-topic”> extract can improve one’s physical and mental health.

Research and surveys show that about 200 million people suffer from bone loss and a substantial number of those people are not elderly people with existing arthritis pain or rheumatoid arthritis . However, issues with bone metabolism , bone density , and bone loss seem to begin in adults aged between 40 to 50 years.

One in three women over the age of 50 are prone to osteoporosis , and approximately one in five men of the same age group struggle with unhealthy bone metabolism and bone loss issues. It is also observed that more women, especially postmenopausal women, may be diagnosed with osteoporosis symptoms .

CBD Oil Benefits for Osteoporosis

Ongoing research into the effects of CBD on bone healing suggests that many patients may benefit from CBD products like CBD cream and hemp seed oil . The hemp seed extract is known to accelerate the body’s ability to heal while enhancing the strength of fractured bones and fragile bones, simultaneously treating bone metabolism .

Osteoporosis could be fatal in its most severe stages. Measures to improve bone strength and bone density are definitely worth considering for alleviating joint pains to provide pain relief .

Marijuana extracts are also known to treat other bone -associated issues like arthritis pain caused by rheumatoid arthritis . CBD products’ ability to suppress receptors triggering pain in the body drastically improves the overall quality of life for those who are not capable of taking regular doses.

Cannabidiol ( CBD ) is a major non-psychoactive constituent of the marijuana plant. It has gained popularity as a potential treatment for intractable joint pain , arthritis pain caused by rheumatoid arthritis , and many other chronic pains in many conditions.

The evidence suggests that CBD provides therapeutic benefits even in certain forms of epilepsy and improves the quality of life. However, the use of CBD products may not always cause pain relief to the consumer.

CBD Products and Usage:

There are several different ways of administering CBD extract . Based on the condition being treated and the appropriate dosage, one of these methods can be used to administer CBD . Some common forms of CBD include:

  1. CBD Oil and CBD cream : CBD oil can be applied or taken directly in the mouth or can even be added to food and drinks. The CBD topical cream can be applied to your body for joint pain relief .
  2. Gummies: CBD gummies are a discrete and convenient method of reaping the benefits of the cannabis plant .
  3. CBD capsules: These generally come in the form of soft gels or pills which are infused with CBD . These may also be abused rather easily. However, they are very convenient.
  4. CBD topicals: People generally use CBD topical creams for localized pain and skin conditions.
  5. CBD vape oils : CBD vape oil generally refers to any vape juice containing CBD . CBD is a derivative in medical cannabis and hemp plants and has been shown to provide relief to several ailments as well as providing pain relief .
  6. CBD tincture : These are alcohol-based extracts that use alcohol to steep the cannabis plant .

Benefits of CBD Oils for Osteoporosis:

There are several medical benefits from the use of the extract of medical cannabis . CBD should be used by combining it with other therapies for maximum benefit and efficacy. While CBD may not being a complete cure for osteoporosis , it offers a supportive role when used with other medications and exercises. The benefits of CBD oils include:

  • CBD improves bone density : CBD appears to enhance bone growth and strengthening by accelerated osteoblast formation. Researchers believe that osteoclasts, when activated, speed up bone degeneration. This receptor is called GPR55. CBD explicitly blocks the activation of this receptor, reducing osteoclast activity.
  • Ease pain and inflammation: CBD reduces inflammation and provides pain relief . It has been used by people for relieving chronic pain caused by osteoarthritis and osteoporosis.
  • CBD regulates hormonal imbalance: The endocannabinoid system may be stimulated with the use of CBD , a cannabinoid produced by the marijuana plant. CBD can be used to stabilize hormones like insulin, cortisol, and melatonin.
  • CBD and bone fractures: CBD enhances fracture healing as it stimulates Lysyl Hydroxylase- an enzyme involved with bone healing. CBD stimulates bone -building cells.

Apart from the above benefits, CBD can also be used to treat arthritis or joint pain, anxiety and depression, sleep disorder, migraine, cluster and other headaches, post-traumatic stress disorder (PTSD), nausea, cancer, allergies or asthma, epilepsy, and other seizure disorders, multiple sclerosis (MS), lung conditions, Parkinson’s disease, Alzheimer’s disease, etc.

Risks and Side-effects Associated With CBD Products

Like many treatments and medications, the use of CBD may also come with some risks.

CBD interacts with supplements and other drugs as well. A majority of the CBD products do not have FDA approval yet. This means that they have not undergone thorough tests and trials. Possible risks of using CBD regularly include:

  • Liver damage
  • Interactions with other drugs and alcohol
  • Inability to remain alert
  • Loss of appetite
  • Mood changes
  • Reduced fertility in men

There has been an exponential growth in the interest of using CBD as a therapy or treatment. Patients must ask a healthcare professional for advice regarding which CBD product to use and how to use it.

They must also research to make sure that they are following the regional and local laws. An immense amount of research is necessary to determine all the effects of CBD on various diseases; however, the treatment of osteoporosis using CBD looks promising. When combined with a healthy diet plan and exercises for osteoporosis, it may help you live well with osteoporosis.

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